In his second inning of work, Penny shut the Dodgers down by striking out the side, which included the second of the game for Ethier. Frias remained on the mound for the fifth as the Dodgers otherwise inserted multiple players from the bench.
With two on and one out, Ramirez double to the left-center field gap to score two runs and extend the White Sox’s lead to 6-1. Frias then got Flowers swinging to end the inning with his fifth strikeout of the game.
In his second at-bat, Pederson collected his second hit on the day as he led off the bottom of the fifth with a double to center field that hit off the wall — coming against left-hander Eric Surkamp nonetheless.
However, Pederson was then stranded by Chris Heisey and Kiké Hernandez and the Dodgers continued to trail, 6-1 at the end of five innings. Sergio Santos emerged from the revolving door that was the Dodger bullpen on Wednesday and retired the side in order in the sixth.
In the bottom half of the inning, O’Koyea Dickson turned on a 1-0 pitch for a solo home run that ever so slightly cut into the Dodgers’ deficit, making the score 6-2. Adam Liberatore pitched a scoreless seventh inning for the Dodgers, who loaded the bases in the bottom of the seventh with one out, but were only able to push across one run.
Darnell Sweeney and Alex Guerrero hit back-to-back singles with no outs in the ninth to set the table for Corey Seager. In his second at-bat of the game, Seager hit an RBI-single to right field that pulled the Dodgers within two runs of the White Sox.
A Kyle Jensen sacrifice fly put runners on the corners with one out for Hernandez, who went down swinging. With the Dodgers down to their final out, Scott Schebler grounded out to end the game and they fell to the White Sox, 6-4.
The loss marked the third-consecutive year the Dodgers dropped the first game on their spring schedule.
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